The past 10 years have seen major advances in our understanding of several key areas of research on the pathogenesis of Type 1 diabetes (T1D) in both man and the principal animal model, the nonobese diabetic (NOD) mouse. With four videos I have attempted to provide a comprehensive overview of the etiology and immunology of T1D and discussed therapeutic strategies that are currently undertaken.
Professor at University P.M. Curie, Paris , France and Guest Professor at Karolinska Institut, Stockholm, Sweden
TEACHING ACTIVITIES (themes)
Physiology/Metabolism and cell biology courses to Master Science and PhD students
Receptors & intracellular signaling: GCPR, RTK, RSTK & Nuclear receptors.
Cell-cell & cell-extracellular matrix interactions.
Glucose homeostasis :physiological and pathophysiological aspects.
Integrative organ cross-talk (metabolic substrates & signalling molecules)
Type 2 diabetes: glucose and lipid metabolism in muscles liver and adipose tissue
Type 1 diabetes: a chronic autoimmune disease
Obesity: regulation of the energy balance: hypothalamic feeding circuits and
peripheral signals (adipocyte, gut, pancreas)
Integrative role of p53/c-Myc/HIF in Warburg effect
How do cancer cells perform metabolic trickery ?
Genome instability and cancer
Epigenetic influences and diseases
Tracer utilization in biology (metabolic studies)
Evolution of concepts in biology
Handbook of Cell Biology (Website): 440 pages